RT Journal Article
SR Electronic
T1 Using low-intensity pulsed ultrasound to stimulate the consolidation of rib fractures: An experimental study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1924
VO 44
IS Suppl 58
A1 Mustafa Calik
A1 Saniye Goknil Calik
A1 Halim Yilmaz
A1 Gulten Karaca
A1 Hasan Esen
A1 Mustafa Cihat Avunduk
A1 Hidir Esme
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/1924.abstract
AB Objective:In this study we investigated the effect of low-intensity pulsed ultrasound (LIPUS) on fracture healing in rat ribs.Methods:72 male Wistar-Albino rats were randomly distributed in 3 equal groups, each including 24 subjects. To simulate a fracture; left thoracotomy was performed under general anaesthesia and a 0.5 cm segment was removed from the ribs. After 24 hours of surgery LIPUS began to be implemented according to the groups. Group 1 served as control for the observation of normal bone healing. LIPUS was applied at a doses of %20 (2 msn pulse-8 msn pause) 100 mW/cm2 and %50 (5 msn pulse – 5 msn pause) 200 mW/cm2 for 6 minutes per day respectively in group 2 and 3. Eight animals from each group were sacrificed at 2, 4 and 6 weeks for further assessment. We analysed histologic changes in the bone.Results:Although no statistical difference was noted for osteoblasts, osteoclasts, new bone formation and lymphocytes among all groups; histologic consolidation was significantly increased by LIPUS. In our study while LIPUS stimulates osteoblastic, osteoclastic and new bone formation, inhibits lymphocyte infiltration.Conclusion:In accordance with the literature, LIPUS either used in lower or higher doses stimulates the consolidation of rib fractures. The most prominent improvement was observed in 200 mW/cm2 group after long term follow-up. Accelerating the natural healing process in patients with rib fractures will be able to treat more effective, short and low cost treatment.