RT Journal Article SR Electronic T1 Comparison of tuberculin test and Diaskintest® in the diagnosis of tuberculosis in children JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4435 VO 42 IS Suppl 57 A1 Natalia Korneva A1 Anna Starshinova A1 Julia Ovchinnikova A1 Irina Dovgaliuk A1 Peter Yablonskiy YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P4435.abstract AB Russia is the country with a high burden of tuberculosis and routine BCG vaccination at birth. Screening of tuberculosis in children by tuberculin skin test (TST) provides low information, because almost all children have positive results of TST.Objectives. The aim of this study is to compare specificity and sensitivity of tuberculin skin test (TST) vs Diaskintest ® (DST) in diagnosis of tuberculosis in children.Materials and Methods. 249 patients from 3 to 14 years old (with a mean age 8,7 years) were examined during 2009-2012 at children's phthisiopulmonology department. All children were divided in two groups: first one – 154 (61.8%) patients with TB and second one – 95(38.2%) healthy children. All patients underwent the TST and DST.Results: The results of TST and DST in two groups are showed in the table.View this table:The results of TST and DSTThe results of TST and DSTTST I group (154) II group (95) DST I group (154) II group (95Low (<10 mm) 6.5% (10) 20.0% (19) negative 16.9% (26) 59% (56)Medium (10-15 mm) 49.3% (76) 55.8% (53)) doubtful 3.5% (5) 15.7% (15)High (≥15 mm) 44.2% (68) 24.2% (23) positive 80.0% (123) 25.3% (24)Results demonstrate that specificity and specificity of DST were significantly higher in comparison with TST: sensitivity (80.0% vs 44.4%) and specificity (59.0% vs 20.0%).Conclusions: It seems that the DST is a more reliable method for the diagnosis of TB in children in comparison with TST.