TY - JOUR T1 - Physiological correlates to physical activity in obese patients with obstructive sleep apnea (OSA) JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P3975 AU - J.C. Rambert AU - R. Rusca Mestre AU - M. Croteau AU - S. Gorain AU - B. Wuyam AU - R. Tamisier AU - P. Levy AU - F. Maltais AU - J.L. Pépin AU - I. Vivodtzev Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P3975.abstract N2 - Background: Obesity and OSA are closely interconnected conditions both leading to reduced exercise tolerance and low physical activity. We investigated physiological correlates of spontaneous physical activity in obese OSA.Methods: 38 obese CPAP-treated OSA (age = 53 ± 3 years; BMI= 38 ± 3 kg/m²) consecutively included in a larger randomized multicenter study performed 5-day actigraphy as well as measurements of pulmonary function, body composition, quadriceps and respiratory muscle strength, and exercise tolerance (six-minute walking distance -6MWD- and maximal aerobic capacity on cycloergometer). Quality-of-life was assessed by the SF-36 questionnaire and sleepiness by the Epworth questionnaire.Results: The mean number of step per day was 7182 ± 2594 and the mean intensity of physical activity was 1.1 ± 0.1 METS, with a mean total energy expenditure of 3123 ± 499 kcal/day. The number of steps per day was correlated with FEV1, (r = 0.38, p = 0.02), Epworth score (r = -0.31, p = 0.06), VO2peak (r = 0.30, p = 0.06) and 6MWD (r = 0.38, p = 0.06). The number of METS tended to correlate with maximal workload (r = 0.32; p = 0.06) and VO2peak (r = 0.30, p = 0.08). IMC, fat-free-mass and perception of dyspnea and leg discomfort during exercise did not influence physical activity.Conclusion: Pulmonary function and sleepiness may significantly influence the number of step per day in obese OSA although the intensity of physical activity appears to be further impacted by exercise capacity. ER -