PT - JOURNAL ARTICLE AU - Gokay Gungor AU - Zuhal Karakurt AU - Huriye Berk Takir AU - Cuneyt Salturk AU - Ruya Evin AU - Feyza Kargin AU - Nalan Adiguzel AU - Merih Balci AU - Özlem Mocin TI - Patients with chronic hypercapnic respiratory failure using home noninvasive mechanical ventilation: Is it better for pulmonary performance? DP - 2013 Sep 01 TA - European Respiratory Journal PG - P5113 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P5113.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P5113.full SO - Eur Respir J2013 Sep 01; 42 AB - BACKGROUND:Acquiring six- minute walk test (6MWT) data from patients undergoing non-invasive mechanical ventilation due to chronic hypercapnic respiratory failure (CHRF) is limited in our country. We aimed to assess any benefit to the respiratory function (include 6MWT) by using long term non-invasive home ventilation (home NIV) due to CHRFMETHODS:This was prospective descriptive cohort study. The 6MWT was performed in patients using home NIV in 12 months intervals in a tertiary teaching hospital respiratory intensive care unit out-patient clinic. Diagnoses were grouped as chronic obstructive lung disease (COPD), obesity hypoventilation syndrome (OHS), kyphoscoliosis and parenchymal lung disease (PLD). Twelve months of the 6MWT values, arterial blood gas, spirometry values were summarized in the diagnosis group.RESULTS:The 6MWT was performed in 85 patients (n=20, COPD; n=34, OHS; n=17, kyphoscoliosis; n=14, PLD) in 12 months intervals. The median 6MWTm, PaCO2mmHg, PaO2/FiO2 in 12 m intervals: COPD:335/354m, 47/49mmHg, 285/315; OHS:314/312m, 46/49mmHg, 300/320; Kyphoscoliosis:420/453m, 50/45mmHg, 320/365; PLD:333/375m, 46/47mmHg, 273/340 respectively. Spirometry values of all diseases group except kyphoscoliosis showed improvement.CONCLUSIONS:Patients using home NIV due to CHRF with COPD, OHS, kyphoscoliosis and parenchymal lung disease have opportunities to slow the progression of diseases and have better pulmonary functions.