TY - JOUR T1 - Smoking cessation in asthmatic patients JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P4942 AU - Segismundo Solano Reina AU - Lidia Perera López AU - Paz Vaquero Lozano AU - Raquel Solano Garcia-Tenorio AU - Teresa Lopez Ruiz AU - Carlos A. Jiminez Ruiz AU - Jose Ignacio de Granda Orive Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P4942.abstract N2 - Introduction:There is a lot of evidence that smoking is an aggravating factor in asthma.Objective:Evaluate smoking cessation abstinence rates in smokers with asthma treated with drug therapy, combined with brief counseling.Material and Methods:It conducted a descriptive, longitudinal and prospective study, from January 2010 to October 2012. All patients underwent clinical history of smoking. A total of seven visits were conducted (baseline, and at weeks 2nd and 4th and at months 2nd, 3rd, 6th and 12th). Smoking abstinence was confirmed by validation of exhaled CO (<10 ppm).Results:We included 128 patients, 98 (76.5%) women and 30 (23.5%) males, mean age: 41.14 (± 10.61) years. Mean number of cigarettes smoked per day: 23.76 (± 9.33). FTND-score Mean: 7.08 (± 1.20), mean CO: 25.26(± 12, 64)ppm. 53% of the subjects smoked their first cigarette five minutes after waking up and 32% 30 minutes after waking up.Considering the treatment used, the abstinence rate at week 52 was:Vareniclina: 58%. Nicotine patches: 49% and bupropion: 45%.Conclusions:• More females than males among the participants.• The average consumption of cigarettes per day is high.• Physical dependence severe, more than 7 points in the FTND-score and 88% smoked their first cigarette within half an hour.• The highest abstinence rate was obtained by varenicline (58%), then nicotine patches (49%) and bupropion (45%).• All medications were well tolerated and safe. ER -