RT Journal Article SR Electronic T1 Outcomes of bedside talc slurry pleurodesis for malignant pleural effusions: A retrospective analysis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2933 VO 42 IS Suppl 57 A1 Rina Adhikary A1 Dipansu Ghosh A1 Elankumaran Paramasivam A1 Matthew Callister YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P2933.abstract AB IntroductionCurrent guidelines recommend either administration of talc slurry via an intercostal drain or talc poudrage by thoracoscopy for the treatment of symptomatic malignant pleural effusions. Published success rates for bedside pleurodesis range from 60 - 95%, however anecdotally these rates are more commonly at the lower end of the spectrum in clinical practice. The issue is complicated by lack of standardized definition of “success” making it difficult to compare different studies. We explored the outcomes of talc pleurodesis in our setting.MethodsAll patients undergoing talc pleurodesis from February 2009 to April 2011 were included. A retrospective analysis of their hospital records and thoracic imaging was undertaken. Primary outcomes were fluid recurrence & need for further interventions.Results41 patients underwent bedside pleurodesis for malignant pleural effusion; 25 for lung malignancy and 16 for other malignancies. 15 patients required further interventions (repeat drainage, VATS, PleurX drain, etc.) 26 (63%) patients did not require further intervention; however fluid re-accumulation was noted in 21 (51%) patients.View this table:Table 1Conclusions63% of patients required no further intervention; this success rate is comparable with other published studies accepting the difficulty of a direct comparison, but is lower than talc poudrage (80 - 90%). This raises the issue whether thoracoscopic pleurodesis should be the intervention of choice in more patients.