RT Journal Article SR Electronic T1 Non-invasive ventilation for respiratory failure in pneumonia- Outcomes in a university teaching hospital JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2481 VO 42 IS Suppl 57 A1 Arun Lakhanpal A1 Apollinaris Kwok A1 Sizheng Zhao A1 Shankaranarayana Venkataramana Nagaraja A1 Gerard Andrew Dempsey YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P2481.abstract AB Respiratory failure in pneumonia is conventionally treated with invasive mechanical ventilation(MV). Non-invasive ventilation(NIV) has been shown to reduce intubation rates, length of stay(LOS) and improve survival rates in the Intensive Care Units1,2. We analysed the University Hospital Aintree Critical Care database retrospectively from January 2009 – July 2012 for all patients requiring ventilatory support for respiratory failure due to pneumonia. Data was recorded on mode of ventilation[NIV, Continuous Positive Airway Pressure (CPAP) & Bi-level Positive Airway Pressure (BiPAP) and MV], APACHE 2 score, mortality and LOS on the unit in all cases.Results - 398 patients satisfied the inclusion criteria. There were 233 males and 165 females. Mean age-63.5 years (Range-18 to 92 years). Results are presented in table 1.View this table:Table 1Conclusion- Survival within the group that received MV was 44%, NIV-68%, NIV trial then MV- 79% and significantly greater in those who received NIV(p<0.05). More controlled studies are needed to identify the criteria for patient selection and risks of failure.References:1. Non Invasive Mechanical Ventilation in pneumonia. Katerina Markopoulou. Pneumon. 2009; 22(Suppl 2):62-632. Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Carrillo A, Gonzalez-Diaz G, Ferrer M,et al.Intensive Care Med. 2012 Mar;38(3):458-66.