PT  - JOURNAL ARTICLE
AU  - Arun Lakhanpal
AU  - Apollinaris Kwok
AU  - Sizheng Zhao
AU  - Shankaranarayana Venkataramana Nagaraja
AU  - Gerard Andrew Dempsey
TI  - Non-invasive ventilation for respiratory failure in pneumonia- Outcomes in a university teaching hospital
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2481
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2481.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2481.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Respiratory failure in pneumonia is conventionally treated with invasive mechanical ventilation(MV). Non-invasive ventilation(NIV) has been shown to reduce intubation rates, length of stay(LOS) and improve survival rates in the Intensive Care Units1,2. We analysed the University Hospital Aintree Critical Care database retrospectively from January 2009 – July 2012 for all patients requiring ventilatory support for respiratory failure due to pneumonia. Data was recorded on mode of ventilation[NIV, Continuous Positive Airway Pressure (CPAP) & Bi-level Positive Airway Pressure (BiPAP) and MV], APACHE 2 score, mortality and LOS on the unit in all cases.Results - 398 patients satisfied the inclusion criteria. There were 233 males and 165 females. Mean age-63.5 years (Range-18 to 92 years). Results are presented in table 1.View this table:Table 1Conclusion- Survival within the group that received MV was 44%, NIV-68%, NIV trial then MV- 79% and significantly greater in those who received NIV(p<0.05). More controlled studies are needed to identify the criteria for patient selection and risks of failure.References:1. Non Invasive Mechanical Ventilation in pneumonia. Katerina Markopoulou. Pneumon. 2009; 22(Suppl 2):62-632. Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Carrillo A, Gonzalez-Diaz G, Ferrer M,et al.Intensive Care Med. 2012 Mar;38(3):458-66.