TY - JOUR T1 - Factors of improvement of dyspnoea, exercise capacity, and quality of life in COPD patients undergoing an outpatient pulmonary rehabilitation JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2227 AU - Marie-Cécile Fournier AU - Thomas Lesuffleur AU - Alexandre Touvron AU - Michel Cabillic AU - Arnaud Cavailles AU - Jean-Benoit Hardouin AU - Arnaud Chambellan Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2227.abstract N2 - Pulmonary rehabilitation (PR) represents the optimal way to improve COPD patients, but inclusion criteria of success remain challenging.Aim: to identify factors of improvement of patients at the beginning of an outpatient PR.Methods: 94 consecutive COPD patients were included. After complete assessment, they underwent a 3 week’s physical training and therapeutic education at the hospital. This was followed by 20 physical sessions supervised by the patient’s physiotherapist. The patients were evaluated at 6 months and one year. The logistic regression was used to identify the independent predictors of success to PR, defined by the MCID for dyspnoea (mMRC scale), the 6 minute walk distance (6MWD), and the Saint George’s Respiratory Questionnaire (SGRQ) total score at baseline.Results: Patients who improve the mMRC scale had a higher level of dyspnoea (OR=4.92, 2.35 to 10.32 CI 95%), were treated by tiotropium (OR=6.43, 1.71 to 24.10), were not frequent exacerbators (OR=4.04, 1.27 to 12.88), and reached a higher VO2max (OR=1.09, 1.04 to 1.15). The only variable identified for 6MWD improvement was not to live alone (OR=9.19, 1.16 to 73.02). Patients who improve the SGRQ score had a higher FEV1 (OR=1.06, 1.01 to 1.11), a higher level of dyspnoea (OR=2.12, 1.05 to 4.28), a worse SGRQ score (OR=1.11, 1.04 to 1.18), a lower CRP (OR=4.07, 1.15 to 14.39), and were more prone to have a 6MWD>350 m (OR=9.72, 1.92 to 49.24).Conclusion: Predictors of improvement in COPD patients undergoing an outpatient PR differ from each dimension. They should be evaluated separately with the patient's perspectives to better define the components of success to PR. ER -