RT Journal Article
SR Electronic
T1 Assessment the dependence between nutritional status and functional damage of the lungs as well as prognosis in BODE index in COPD patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3678
VO 42
IS Suppl 57
A1 Barbara Kuznar-Kaminska
A1 Marcin Grabicki
A1 Beata Brajer-Luftmann
A1 Halina Batura-Gabryel
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P3678.abstract
AB Cachexia is systemic manifestation of COPD, that can influence on disease outcome and patients prognosis. Aim of study was assessment the dependence between nutritional status and functional damage of lungs 2.Evaluation the connection between cachexia parameters and disease prognosis in BODE index. 114 patients – 60,5% males and 39,5% females, mean age 65,6 +/- 9,3 in different stages of stable COPD participated in the study. Nutritional status was evaluated by BMI, FMI, FFMI, MMI using bioimpedance method. Functional tests – spirometry, bodypletysmografy and diffusion test were performed in order to measurment of FEV1, RV, ITGV, RV/TLC, DLCO. Each participant was assessed in BODE index. Malnutrition assessed with BMI, FFMI was found in 7,02% and 16,66 % of COPD patients, respectively. In most patients 52,63% very severe stage of obstruction was found. It was observed dependence between parameters of nutritional status and stage of the obstruction in subgroup of patients with cachexia BMI, FFMI, MMI & FEV1 (r=0,51, 0,36, 0,42, respectively). BMI and FMI inversely correlated with indicators of lung hyperinflation in subgroup of malnourished patients BMI & RV, ITGV, RV/TLC (r = -0,65; -0,72; -0,48 respectively), but not for other parameters of cachexia: FFMI, MMI. It was confirmed inversely correlation between BMI and MMI with prognosis in BODE index, better found in group of patients with malnutrition BMI, MMI & BODE (r = -0,67 -0,60), respectively.1. Presence of cachexia is an important parameter affecting functional worsening of lung parameters. 2. Malnutrition is negative prognostic factor measured in BODE index in group of COPD patients.