TY - JOUR T1 - Disease severity in RSV and non-RSV bronchiolitis: Usefulness in clinical decision-making JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P1878 AU - Fabiola Stollar AU - Gabriel Alcoba AU - Alain Gervaix AU - Constance Barazzone Argiroffo Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P1878.abstract N2 - Background: Bronchiolitis morbidity remains a major health problem and identifying risk factors for disease progression can help in clinical decision-makingAims: To assess differences in disease severity between RSV (respiratory syncytial virus) and non-RSV bronchiolitis during two consecutive RSV seasons (2010-2012).Methods: Medical records of all patients <1 year admitted to the Emergency Department with bronchiolitis were reviewed. We compared length of hospital stay (LOS), admission to intensive care unit (ICU), oxygen and nasogastric tube (NGT) need and duration, and mortality. We divided the analysis into two models (Model 1: all episodes; Model 2: hospitalized) to avoid bias related to our hospitalization criteria (feeding <50% of the required amount, SpO2 of <92% in air).Results: We analyzed 479 patients (317M:162F) and 582 episodes of bronchiolitis. In the two models the number of children who required supplemental oxygen, the LOS and length of oxygen therapy were significantly higher for the RSV episodes. In model1 the number of children who required ICU (odds ratio[OR]=6.9; 95% confidence interval[CI]:2.4-20.0), non invasive ventilation (OR=10.6; 95%CI: 3.0-38.5) and a NGT (OR=17.7; 95%CI: 10.0-31.3) was significantly higher in the RSV group. In model2 the length of NGT was longer for children in the RSV group (5.4±4.7 vs. 3.3±2.4; P=0.01). However, the need for intubation did not differ between groups in both models. No death was documented.Conclusions: RSV episodes were more severe compared to non-RSV. Our findings show that viral diagnosis is useful not only for cohorting babies but also to determine the prognosis and to assist in clinical decision-making. ER -