PT - JOURNAL ARTICLE AU - Ekaterina Kochetova TI - The decrease of nutritional status and increasing of the risk of osteoporotic fractures in patients with chronic obstructive pulmonary disease (COPD) DP - 2013 Sep 01 TA - European Respiratory Journal PG - P2159 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P2159.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P2159.full SO - Eur Respir J2013 Sep 01; 42 AB - Objective: study of nutritional status, assessment of body mass index (BMI) and the risk of osteoporotic fractures in patients with COPD.Materials and Methods: 120 patients COPD were observed. The investigated group was made by the men with long experience of smoking. The average age was 60.2 ± 5.9 years. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Research of bone mineral density was studied with the method x-ray absorbtiometry with the densitometer « Lunar DPX-NT». The assessment of risk of osteoporotic fractures were calculated by means of the computer program FRAX. The body mass index (BMI) in patients was observed. The decrease of BMI <18.5 shows the deficit of the weight. Results: The average BMI in patients with COPD of 2nd stage was 28.21 ± 12.68, BMI in patients with COPD of 3rd stage was 25.18± 6.29. Among patients with COPD of 2nd stage the number of patients with the decrease of BMI was 6.97%, among patients with COPD of 3rd stage the number of patients with the decrease of BMI was 16.98%, among patients with COPD of 4th stage the number of patients with the decrease of BMI was 18.8%. The deterioration of stage of COPD was connected with a significant increase of the number of patients with the decrease of BMI (p<0.05). The correlation coefficient between BMI and risk of major osteoporotic fracture was -0.39 (p<0.05), the correlation coefficient between BMI and the risk of hip fracture was -0.59 (p<0.05).Conclusions: BMI decrease has an important role in increasing the risk of osteoporotic fractures in patients with COPD.