RT Journal Article SR Electronic T1 Validity and reliability evidence of the nijmegen questionnaire in astma JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1307 VO 42 IS Suppl 57 A1 Eirini Grammatopoulou A1 Emmanouil Scordilis A1 Afrodite Evangelodimou A1 Aikaterini Haniotou A1 Arietta Spinou A1 Nikolaos Tsamis A1 Konstantinos Grigoriadis A1 Dafni Antoniadou A1 Maria Xyki A1 Vlassia Belibassaki YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P1307.abstract AB IntroductionThe Nijmegen Questionnaire (NQ) is the most commonly used screening tool for hyperventilation. The validity of the NQ has not been reported for Greek asthma out-patients.AimReport the validity evidence of the Nijmegen Questionnaire in asthma.Methods162 Greek asthma out-patients (86 with mild and 76 moderate asthma) participated in the study. Hyperventilation was assessed using NQ and clinical measures such as breath holding time (BHT), respiratory rate (RR) and end-tidal CO2 (ETCO2). Construct validity was tested through factor analysis and cross-sectional validity through correlations of the NQ score with BHT, ETCO2 and RR (Pearson’s r correlation coefficient).ResultsExploratory factor analysis for the three pre-hypothesized factors of the 16 item NQ showed low factor loadings which led to a principal component analysis (PCA) for NQ. The PCA revealed a one-factor solution with 11 items (Q1, Q2, Q4, Q5, Q6, Q7, Q8, Q9, Q11, Q13, and Q16). The one-factor solution revealed a total of 58.86% of explained variability and a high Cronbach alpha (a = .92). These findings were supported by confirmatory factor analysis for the 11 items NQ model [χ2 = 149.90, df 44, p<.01, χ2 /df ratio = 3.407, CFI = .99, IFI = .99, AGFI = .98, SRMR = .14, RMSEA = .14.]. Cross-sectional validity testing showed moderate correlations of the NQ score with ETCO2 (r = -.77, p< .001), RR (r = .66, p< .001), BHT (r = -.65, p< .001).ConclusionThe NQ was valid and reliable in the present sample with asthma.View this table:Loadings and communalities of the 11 item NQ model