RT Journal Article
SR Electronic
T1 Equivalence of an innovative multidose salmeterol/fluticasone dry powder inhaler vs comparator in paediatric asthma
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4296
VO 42
IS Suppl 57
A1 Piotr Kuna
A1 Ingolf Gath
A1 Ursula Thyroff-Friesinger
A1 Spencer Jones
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4296.abstract
AB This study evaluated efficacy and safety of an innovative dry powder inhaler (DPI – Sandoz) vs Seretide™ Accuhaler™ (GSK) containing 50 μg salmeterol and 100 μg fluticasone per actuation.A double-blind, double-dummy, multicentre, randomized, 2-arm parallel group study in children with persistent moderate asthma with a 2-week washout period and 12 weeks of active treatment; twice daily inhalation of a single actuation from an active and placebo device.The innovative DPI and Seretide™ Accuhaler™ gave comparable results in children (6–11 years) across all endpoints.View this table:The incidence of adverse events with a suspected drug relationship was very low and comparable between treatments.