PT  - JOURNAL ARTICLE
AU  - Catarina Dias
AU  - Ricardo Reis
AU  - Catarina Oliveira
AU  - Isabel Candelaria
AU  - Catarina Ferreira
AU  - Amélia Estevão
AU  - Fernando Barata
TI  - CT-guided transthoracic biopsy of pulmonary lesions: 4 years of experience
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2318
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2318.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2318.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - The aim of our study was to evaluate the type, location and depth of the lesion, complication rate and diagnostic accuracy of CT-guided fine needle aspiration biopsy (FNAB) and core biopsy (CB) of lung lesions. We reviewed the CT-guided needle biopsies performed in the Radiology Department of Centro Hospitalar e Universitário de Coimbra – Hospital Geral during a four year period (December 2008-December 2012) in patients with suspected malignant lesions. The final diagnosis was based on histopathology after surgical resection or follow-up and response to treatment. The results were statistically analysed using SPSS 20.0. A total of 150 FNAB/CB were considered, 10 were excluded. Sixty five per cent of FNAB/CB were performed on male, median age of 67,5 years. Complications occurred in 5.7% of the procedures, hemorrhage was seen in 3.5%, hemoptysis in 0.71% and pneumothorax in 1.4%, without drainage needed. FNAB was performed in 14.3%, CB in 83.6% and both in 2.1%. The complication rate was significantly affected by the depth of location of the lesion (p<0.05). The pathological examination demonstrated 60% of the cases were neoplastic, 25.2% nonneoplastic. In 14.8% of the lesions, the sample was inconclusive for diagnosis. The overall diagnostic yield was 85.2% and 60% for neoplastic lesions. We could obtain diagnostic confirmation (clinical or by surgery) in 86.33% of the cases. The sensitivity, specificity, PPV and NPV for neoplastic lesions was 96.5%, 100%, 100% and 92.3% respectively. CT-guided transthoracic biopsy is very sensitive, specific and safe in diagnosing malignancy. The complication rate was significantly affected by the depth of the lesion.