RT Journal Article SR Electronic T1 Factors affecting treatment success in community acquired pneumonia (CAP) JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P299 VO 42 IS Suppl 57 A1 Canan Gündüz A1 M. Sezai Tasbakan A1 Abdullah Sayiner A1 Aykut Çilli A1 Burcu Karaboga A1 Oguz Kilinç A1 Öznur Kiliç A1 Aysin Sakar Coskun A1 Cemile Çetinkaya A1 Armagan Hazar A1 Fatma Tokgöz YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P299.abstract AB Objective: Community acquired pneumonia is a leading cause of morbidity and mortality despite appropriate antibiotic treatment. The aim of this study is to evaluate the factors affecting treatment success in community acquired pneumonia.Materials and Methods: The factors affecting treatment success were analyzed in 537 patients (median age 66.1±15.8, 365 male) registered to Turkish Thoracic Society Respiratory Infections Study Group pneumonia database with treatment results. Patients with full and partial response (n=477) were included in the group with treatment success. Patients who died or with no treatment response (n=60) were included in the group with treatment failure.Results: In our study examining treatment response; low number of neutrophils (5989.9±6237.3 vs. 8495.6±7279.5/mm3), high blood urea levels (66.1±42.1 vs. 51.2±38.2 mg/dL), high PSI (123.3±42.6 vs. 96.3±32.9), high CURB-65 scores (2.7±1.2 vs. 2.2±0.9), low PaO2/FiO2 ratio (216.3±86.8 vs. 269.9±65.6), presence of multilobar (p=0.002) and bilateral (p<0.001) radiologic consolidations were found related to treatment failure. PSl (p<0.001) and PaO2/FiO2 (p<0.001) were observed to be independent parameters affecting treatment results in multivariate lineer regression analysis.Conclusion: In community acquired pneumonia, the risk of treatment failure is high in patients with high pneumonia severity index score and with respiratory failure. Effective treatment and close monitoring are required for these cases.