PT  - JOURNAL ARTICLE
AU  - Canan Gündüz
AU  - M. Sezai Tasbakan
AU  - Abdullah Sayiner
AU  - Aykut Çilli
AU  - Burcu Karaboga
AU  - Oguz Kilinç
AU  - Öznur Kiliç
AU  - Aysin Sakar Coskun
AU  - Cemile Çetinkaya
AU  - Armagan Hazar
AU  - Fatma Tokgöz
TI  - Factors affecting treatment success in community acquired pneumonia (CAP)
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P299
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P299.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P299.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Objective: Community acquired pneumonia is a leading cause of morbidity and mortality despite appropriate antibiotic treatment. The aim of this study is to evaluate the factors affecting treatment success in community acquired pneumonia.Materials and Methods: The factors affecting treatment success were analyzed in 537 patients (median age 66.1±15.8, 365 male) registered to Turkish Thoracic Society Respiratory Infections Study Group pneumonia database with treatment results. Patients with full and partial response (n=477) were included in the group with treatment success. Patients who died or with no treatment response (n=60) were included in the group with treatment failure.Results: In our study examining treatment response; low number of neutrophils (5989.9±6237.3 vs. 8495.6±7279.5/mm3), high blood urea levels (66.1±42.1 vs. 51.2±38.2 mg/dL), high PSI (123.3±42.6 vs. 96.3±32.9), high CURB-65 scores (2.7±1.2 vs. 2.2±0.9), low PaO2/FiO2 ratio (216.3±86.8 vs. 269.9±65.6), presence of multilobar (p=0.002) and bilateral (p<0.001) radiologic consolidations were found related to treatment failure. PSl (p<0.001) and PaO2/FiO2 (p<0.001) were observed to be independent parameters affecting treatment results in multivariate lineer regression analysis.Conclusion: In community acquired pneumonia, the risk of treatment failure is high in patients with high pneumonia severity index score and with respiratory failure. Effective treatment and close monitoring are required for these cases.