RT Journal Article SR Electronic T1 Early detection of undiagnosed COPD in general practice; the yield of population-based screening according to socioeconomic status JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P263 VO 42 IS Suppl 57 A1 Joseph Dirven A1 Huibert Tange A1 Jean Muris A1 Onno van Schayck YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P263.abstract AB Background. The burden of chronic obstructive pulmonary disease (COPD) is high. Health benefits can be gained in primary care by early detection and preventive measures.Aim. To determine the effectiveness of a population-based screening procedure including a risk questionnaire and spirometry testing. To compare two strategies of providing this procedure in different socioeconomic settings.Method. A cluster-randomised controlled trial among all 40-70 years of age in 16 family practices. Practices were randomized on strategy and stratified on socioeconomic profile. The Respiratory Health Screening Questionnaire (RHSQ) was used. In the practice managed condition, the practice was responsible for the whole procedure. In the patient managed condition patients were responsible for calculating their RHSQ risk score and applying for a spirometry test. Main outcome measure was the rate of COPD diagnoses after screening.Results. In the practice-managed condition more new COPD patients were detected (36%) than in the patient-managed condition (18%). In low-SES practices more high-risk patients were found (16%) than in average-SES practices (9%). Recalculated for a standard Dutch practice (2250 patients) the yield would be 20% increase of known cases.Conclusion. The practice-managed variant of this screening procedure shows a substantial yield of new COPD diagnoses for both low-SES and average-SES practices.