TY - JOUR T1 - Does one year change in quality of life predict the mortality in patients with COPD?: Prospective cohort study JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2393 AU - Yavuz Havlucu AU - Arzu Yorgancioglu AU - Aysin Sakar Coskun AU - Pinar Celik Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2393.abstract N2 - To assess the contribution of the 1 year change in quality of life in predicting the mortality and survival time of a cohort of patients with COPD followed for 9 years.Health related quality of life,St. George Respiratory Questionnaire (SGRQ) and pulmonary function test assessment was done beginning and first year. Mortality will be obtained from hospital records and direct family interviews.Comparisons were performed using independent unpaired t-tests, a nonparametric Mann–Whitney U-test or the Chi-squared test. Cox regression analysis for baseline QoL scores and 1 year change in QoL. Statistical significance is accepted at p<0.05.In this prospective study,218 patients(86.85%) were male and mean age was 65,55(43-82 years). When the begining parameters of dead patients and survived patients were compared, there was a statistically difference according to body mass index, smoking, PFT parameters, and SGRQ scores(p<0.05.). when the beginning paramaters of dead patients due to respiratory reason and due to non-respiratory reasons, there was significant difference according to age and presence of cardiac comorbidty. After cox regression analysis, relative risk of baseline quality of life score was 1,042 (95% CI 1,028-1,057) for all cause mortality and 1,030 (95% CI 1,011-1,050) for respiratory cause mortality but relative risk of one year change in quality of life was 1,175 (95% CI 1,130-1,221) for all cause mortality and 1,214 (95% CI 1,151-1,280) for respiratory cause mortality.Baseline assessment of QoL with change in quality of life in a year is more effective than baseline asessment to predict the any cause and respiratory cause mortality among patients with COPD. ER -