TY - JOUR T1 - Overall survival is significantly higher in sarcoidosis than in IPF patients after lung transplantation JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2688 AU - Hans Henrik Schultz AU - Claus Andersen AU - Daniel Steinbrüchel AU - Elisabeth Bendstrup AU - Michael Perch AU - Jørn Carlsen AU - Martin Iversen Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2688.abstract N2 - BackgroundAmong the current indications for lung transplantation, Sarcoidosis represents 2.5% and idiopathic pulmonary fibrosis (IPF)25%. There are no specific selection criteria regarding lung transplantation for sarcoidosis patients and the criteria are generally assumed to be similar to IPF criteria. The purpose of this study was to compare outcome in lung transplant recipients transplanted for sarcoidosis and IPF.Methods:Single center retrospective study from a national lung transplant center comprising all 620 lung transplants from 1992-2012 including all 25 patients with sarcoidosis and all 53 with IPF. Two IPF patients were excluded, one due to retransplantation, and one because of combined heart and lung transplantation.Results:17 males and 8 females with pulmonary sarcoidosis were transplanted (8 single and 17 double lung transplantation).38 males and 15 females with IPF were transplanted (26 single and 24 double lung transplantation).Overall survival was significantly higher in sarcoidosis patients compared to IPF patients (p=0.042).The estimated TLC of donor were the same (p=.744). Actual TLC of recipient prior to transplantation were lower in the IPF group (p=.009), and the Recipient/donor TLC ratio was lower in the IPF group (P=.008).Conclusion:Patients with sarcoidosis have a significantly higher survival after lung transplantation than patients with IPF.This difference cannot be explained by numbers of acute rejections, recipient age, or estimated TLC in donors, but is due to frequent early deaths in the IPF group. This, seems to be correlated to a lower pretransplant TLC and a lower recipient/donor TLC ratio in the IPF recipients. ER -