PT  - JOURNAL ARTICLE
AU  - Wilawan Thirapatarapong
AU  - Matthew Bartels
AU  - Hilary Armstrong
TI  - Comparison of cardiopulmonary exercise test in COPD patients with and without coronary artery disease
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P1841
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P1841.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P1841.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Background:Coronary artery disease(CAD) is a common concomitant condition in COPD. As COPD and CAD can independently cause reduced exercise capacity, the combination of diseases may compound the abnormality during cardiopulmonary exercise test(CPET).Methods: 54 COPD patients without CAD(COPDnoCAD) were matched to 54 COPD with CAD(COPD/CAD) due to age, sex, BMI and severity of COPD.View this table:Table1-Characteristics and PFTPatients underwent pulmonary function and symptom-limited CPET.Results: Comparing COPDnoCAD with COPD/CAD revealed that exercise capacity, measured by %peak VO2 and %peak watt, was lower in COPD/CAD.Ventilatory response, measured by VE/VCO2, was higher in COPD/CAD, with %peak VO2 and VE/VCO2 correlating to %FEV1 and inversely correlating with %DLCOView this table:Table 2-Correlation of CPET and PFT variablesConclusion: COPD with CAD impairs exercise capacity and gas exchange on CPET. The findings may affect the interpretation of CPET in COPD with concomitant CAD.