RT Journal Article
SR Electronic
T1 The elderly subjects with asthma (ELSA) study. Asthma in subjects ≥65 yrs and its overlap with COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 355
VO 42
IS Suppl 57
A1 Manlio Milanese
A1 Angelo Corsico
A1 Nicola Scichilone
A1 Fabiano Di Marco
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/355.abstract
AB “Asthma in older adults is an increasingly serious health issue and its overlap with COPD has yet to be adequately addressed in management approaches” (from PG Gibson et al. Lancet 2011).Therefore we performed a 6-month observational study on this topic (ELSA Study, N=16 center, n=320 asthmatic subjects). The presence of chronic bronchitis and/or CO diffusion impairment were considered criteria for the diagnosis of overlap with COPD.Results are summarized below. Patients with COPD overlap (27%) were less controlled than asthmatic subjects (18±4 vs 20±4 ACT score, p<0.05), more prone to ≥2 severe asthma exacerbations (18% vs 6% of them, p<0.05) and less frequently users of a LABA/ICS combination (58% vs 74%). Is a more aggressive approach needed in this important subgroup?View this table: