RT Journal Article SR Electronic T1 Tobacco smoking and intellectual functions among teenagers JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1073 VO 42 IS Suppl 57 A1 Anna Sokalska A1 Piotr Szczesny A1 Pawel Holas A1 Joanna Domagala- Kulawik YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P1073.abstract AB The effects of smoking on the central nervous system are still not explored. Carbon monoxide(CO)-tobacco smoke component, is known to disturb neurogenesis during interuteral development. This however did not lead to further studies assessing the influence of smoking on the functions of rapidly developing nervous system of teenagers. This group specifies in comprehensive brain development and it is expected to present effectiveness in intellectual effort.The aim of the study was to confirm the influence of smoking-related CO on the intense brain activity among teenagers of Warsaw collaborated to exposition to CO descended from tobacco smoke.Beck Depression Inventory(BDI), the psychometric tests: Number Connection Test (NCT)A and B (experience usage, problem solving, short and long-term memory), D2 Test, measurement of CO expiratory concentration using Smokelyzer®. The assessed group was consisted of two ranges: 13-16 years old and 17-19 years old teenagers.Medium CO concentration was higher in the older group. The passive smokers quit the addiction less frequently. Those smoking were presenting more frequent respiratory infection. Among smokers more participants shown mild mood disturbances (11-16 points in BDI) and higher predisposition to severe depression (31-40 points). Significantly worse results of NCT-A and B were provided by students with higher CO concentration in the expiratory flow. Passive smokers presented worse NCT-A score.The study showed that measurement of CO concentration can reflect intellectual function. Stunning fact is large number of students diagnosed with high CO level during the busiest hours at school which influences negatively the intellectual effort. Our team is continuing the observations.