PT  - JOURNAL ARTICLE
AU  - Deniz Dilaver
AU  - Samantha S.C. Kon
AU  - Amy L. Clark
AU  - Claire M. Nolan
AU  - Jane L. Canavan
AU  - Sarah E. Jones
AU  - Michael I. Polkey
AU  - William D.-C. Man
TI  - Responsiveness of the clinical COPD questionaire to pulmonary rehabilitation
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P3576
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P3576.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P3576.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - BackgroundThe Clinical COPD Questionnaire(CCQ) is a simple to use health status instrument, takes two minutes to complete and has good psychometric properties (van der Molen T 2003). The minimum clinically important difference is 0.4 points (Kocks 2006), however limited data exists on the responsiveness of the CCQ to pulmonary rehabilitation (PR).AimsTo demonstrate the response of the CCQ to PR in comparison with other well established health status instruments.Methods275 COPD patients referred to an 8-week outpatient PR programme were recruited. CCQ, St George’s Respiratory Questionnaire (SGRQ), COPD Assessment Test (CAT) and the Chronic Respiratory Disease Questionnaire (CRQ) were measured pre and post PR. Paired t tests were used to assess change. Correlations betweeen change in CCQ with change in other health status questionnaires were assessed using Spearman's rank. Effect sizes were calculated using the means and standard deviations of the two groups (pre and post PR).Results219 COPD patients completed PR. Baseline characteristics are presented as mean (SD) or median (25th,75th centiles); Age 71 years (64,76), FEV1 pred 50% (34,65), MRC 3 (2,4), Male : Female 124:95. There was a significant change in all domains of the CCQ and a mean change in total CCQ score of -0.4 (-0.5,-0.2) (p<0.001). Change in CCQ total with PR correlated significantly with changes in all domains of other health status instruments (all p<0.01). The effect size of PR on CCQ was 0.4 compared to CRQ (0.6), SGRQ (0.3) and CAT (0.3).ConclusionThe CCQ is similarly responsive to PR as other commonly used health status instruments. It may be a simple practical alternative to longer questionnaires as an outcome measure.