RT Journal Article
SR Electronic
T1 Comparison of gender-related risk factors for COPD - Results from the Canadian obstructive lung disease (CanCOLD) study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4225
VO 42
IS Suppl 57
A1 Wan Tan
A1 Denis O'Donnell
A1 Shawn Aaron
A1 Darcy Marciniuk
A1 J. Mark Fitzgerald
A1 Robert Cowie
A1 Kenneth Chapman
A1 Paul Hernandez
A1 Don Sin
A1 Francois Maltais
A1 Jean Bourbeau
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4225.abstract
AB Background: COPD is an important disease in women, with an increasing prevalence in developed and developing countries.Objectives: To compare risk factors for COPD by gender in the general population.Methods: The random sample consisted of 5176 people aged 40 years and older from 9 sites in Canada who completed interviewer administered questionnaires on respiratory symptoms and diseases, co-morbidities and health related quality of life and who performed spirometry before and after administration of 200ug of inhaled salbutamol/albuterol. The analysis was performed for 4893 [95%] subjects who had ATS acceptable and repeatable spirometric data. Logistic regression analysis was used to compute adjusted odds ratio [OR, 95%CI] for independent risk factors for men and women.Results: Common independent risk factors for men and women included increasing age, smoking, prior diagnosis of asthma, presence of chronic cough and phlegm, a history of childhood hospitalization for severe respiratory illness and exposure to passive smoking. The overall risk for COPD for women referenced to men in the study population, with adjustment for all risk factors and for pack years of cigarettes smoked, is shown below, by age groups.Conclusions: Men and women have common risk factors for mild to moderate COPD. Women compared with men, did not appear to be at increased risk in the general population.