TY - JOUR T1 - Antibiotics therapy against airway's infections during pregnancy and related problems JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2737 AU - Roman Bontsevich AU - Oleg Golovchenko AU - Vladimir Kulikovsky AU - Mikhail Pokrovsky AU - Tatyana Pokrovskaya AU - Yury Afanasjev Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2737.abstract N2 - The aim of work was to study the frequency of rational antimicrobial prescriptions (AP) against airway’s infections (AI) in pregnant women.Material and methodsWe have been registering the cases of AP in pregnant women against AI during specialized advisory attendances held in 2010-2012 in perinatal center. Medications were earlier prescribed to women in residential antenatal clinics and polyclinics. We have assessed the advisability of such prescriptions and evaluated the safety of prescribed medications.ResultsDuring the study there were registered and analyzed 147 cases of AP against AI in pregnant women. In 59 (40.1%) cases the prescription was regarded as irrational, because patients were most likely infected with virus. In 37 (25.2%) cases the rationality of prescription was regarded as ambiguous as there were not enough data of bacterial infection. In 51 (34.7%) cases the AP was considered adequate as there were found strong symptoms of bacterial infection.In 2 cases (1.4%) a banned medication (ciprofloxacin) was prescribed to patients, in 5 (3.4%) – irrational combination of medications, in 17 (11.6%) – violations of regime were observed (dosage and its frequency).ConclusionsIt was revealed that unduely excessive antimicrobial prescriptions were taken against AI in pregnant women in antenatal and out-patient clinics. At the same time there were no clear evidence of bacterial infection, on the opposite, viral microflora (ARVI, acute bronchitis) was very likely to exist. Besides, the cases of irrational AP, irrational combinations of medications and even singular cases of prescriptions of banned medications were registered. ER -