TY - JOUR T1 - Comorbidity in patients with COPD in Russia JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P3674 AU - Nina Karoli AU - Andrey Rebrov Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P3674.abstract N2 - Comorbidities are frequent throughout the lifespan of COPD patients, and are ultimately responsible for many deaths.The aim of our study was evaluated frequently of comorbidities in patients with COPD.We performed retrospective analysis history of 125 patients with COPD (mean age 54,93±0,63 yrs). We studied all comorbidity diseases in patients with COPD and performed analysis of the Charlson Comorbidity Index (CCI) with W.H. Hall modification. COPD was diagnosed according GOLD criteria. 39.2% was with COPD I-II stage and 60.8% was with COPD III-IV stage.Patients with COPD had 3,49±0,22 chronic comorbidity condition. Cardiovascular diseases are most frequently comorbidities in pts with COPD (MI had 11,2% pts, angina pectoris 13,6%, arterial hypertension 59,2% and heart failure 20,0% pts). CCI was 2,82±0,14 in patients with COPD. CCI in patients with COPD I-II stages was 2,40±0,19 and in pts with COPD III-IV stages was 3,11±0,18 (p<0.01). In group of COPD pts we noted correlations between CCI and age (r=0.76, p<0.001), duration of disease (r=0.48, p<0.01), smoking intensity (r=0.47, p<0.01), SaO2 (r=-0.47, p<0.01) and 6-min. test result (r=-0.38, p<0.05). Also we noted association between CCI and systemic inflammation (leucocytes (r=0.19, p<0.05) and ESR (r=0.25, p<0.05) and Systemic Coronary Risk Evaluation (r=0.54, p<0.001).So comorbidities are frequently in patients with COPD and In conclusion early detection of concomitant diseases in patients with COPD is important and should be considered carefully when initiating therapy. ER -