PT  - JOURNAL ARTICLE
AU  - Necati Citak
AU  - Adnan Sayar
AU  - Muzaffer Metin
AU  - Songül Büyükkale
AU  - Abdulaziz Kök
AU  - Alper Çelikten
AU  - Okan Solak
AU  - Sibel Yurt
AU  - Neslihan Akanil Fener
AU  - Atilla Gürses
TI  - The prognostic significance of metastasis to aortopulmonary lymph nodes in completely resected left lung tumors
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2912
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2912.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2912.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Introduction. The mediastinal staging is the most important prognostic factor in NSCLC without distant metastasis.We investigated the prognostic effect of nodal metastasis in resected NSCLC of the left upper lobe.Methods. Between 1998-2010, 181 patients with proven left lung carcinoma underwent complete resection were retrospectively analysed. The patients were divided into five groups acccording to N status; N0 (n=68, 37.5%), N1single (n=49, 27.1%), N1multiple (n=15, 8.3%), N25,6+ (only metastasized to #5 and/or #6, n=36, 19.9%), N27+ (only metastasized to #7, n=13, 7.2%).Results. The overall 5-year and 10-year survival rates were 55.1% and 35.2%, respectively.The 5-year survivals were as 76.1% for N0, 54.3% for N1 (60.1% for N1single, 36.6% for N1multiple), 20.7% for N2 (24.3% for N25,6+). N2 were the worse prognostic factor when compared with N0/1 (p<0.0001). Patients with N0 had a significantly better survival than those patients with N1 (p=0.006). N1single patients were found to have statistically significant better survival rates with when compared to both N1multiple and N25,6+ (p=0.02, p=0.008, respectively). Patients having involvement of subcarinal lymph nodes had a significantly worse prognosis than those patients with metastases only to aortopulmonary lymph nodes (stations 5 and/or 6) (p=0.02).Conclusion. The metastasis to mediastinal lymph nodes in completely resected left upper lobe NSCLC has a worse prognostic effect on survival. The patients with N0 and N1single were found to have better prognostic rates in comparison with N1multiple and N25,6+. The presence of aortopulmonary lymph nodes have a worse effect on survival.