RT Journal Article
SR Electronic
T1 The influence of continuous positive airway pressure treatment on echocardiographic parameters of systolic and diastolic function of the left ventricle
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2570
VO 42
IS Suppl 57
A1 Milan Sova
A1 Eliska Sovova
A1 Milada Hobzova
A1 Jana Zapletalova
A1 Sona Panakova
A1 Monika Zurkova
A1 Eva Koukalova
A1 Vitezslav Kolek
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P2570.abstract
AB Aim: The aim of this study was to compare echocardiographic parameters of systolic and diastolic function of the left ventricle in patients with obstructive sleep apnea (OSA) before and after one year of continuous positive airway pressure (CPAP) treatment. As a control group we used patients who were not treated.Methods: 78 patients (68 men, average age 52.74 years) with OSA indicated to CPAP treatment were evaluated by echocardiography at the baseline and after one year of CPAP treatment. The control group was comprised of 42 patients (35 men, average age 54.38 years) with OSA not indicated for CPAP treatment. We assessed parameters of OSA severity, chosen parameters of heart function (left ventricle TEI, isovolumic contraction time (ICT), parameters of diastolic function- dopplerometric assessment of mitral valve flow and tissue doppler imaging examination of left ventricle).Results: In patients treated with CPAP we observed statistically significant changes of Epworth sleepiness scale (p<0.0001), apnea-hypopnea index (p<0.0001), average night oxygen saturation (p<0.0001), oxygen desaturation index (p<0.0001), % of sleep time in oxygen saturation < 90% (p<0.0001), left ventricle ICT (p=0.046). The following parameters had not in the comparison with control group changed significantly: left ventricle TEI (p=0.79) and parameters of diastolic function of left ventricle (p=0.406)Conclusion: CPAP treatment does not improve left ventricle TEI or parameters of diastolic function of the left ventricle.