TY - JOUR T1 - Physiologic responses to the incremental shuttle-walk test in adolescents with idiopathic scoliosis JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2529 AU - Evandro Fornias Sperandio AU - Anderson Sales Alexandre AU - Fabíola Pereira Rebouças AU - Liu Chiao Yi AU - Patrícia Rios Poletto AU - Alberto Ofenhejm Gotfryd AU - Milena Carlos Vidotto AU - Victor Zuniga Dourado Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2529.abstract N2 - Exercise limitation has been described in patients with adolescent idiopathic scoliosis (AIS). However, whether the walking performance is impaired in these patients should be elucidated. We aimed to evaluate physiologic responses to the incremental shuttle-walk test (ISWT) in patients with AIS. Twenty-nine patients with AIS and 20 healthy adolescents aged 10-18 years performed two ISWT. During the second test, oxygen uptake (VO2), CO2 production (VCO2), ventilation (VE) and heart rate (HR) were continuously monitored. We assessed the following rates of changes during the ISWT: ΔVO2/Δwalking-velocity, ΔHR/ΔVO2, ΔVE/ΔVCO2, and linearized Δtidal-volume (VT)/ΔlnVE. Forced expiratory volume in 1s (FEV1) and forced vital capacity (FVC) were also assessed. Patients with AIS showed significant lower values of incremental shuttle-walk distance (ISWD: 498 ± 144 vs. 604 ± 85 m), peak VO2 [median (interquartile range), 25 (21-27) vs. 28 (24-33) mL/min/kg], peak VE (43 ± 16 vs. 52 ± 14 L/min) as well as lower FEV1 [2.77 (2.48 to 3.17) vs. 3.33 (3.16 to 3.81) L] and FVC (2.51 ± 0.68 vs. 2.94 ± 0.66 L). Patients also presented significant shalower slope of ΔVT/ΔlnVE (0.32 ± 12 vs. 0.45 ± 16), i.e., worse breathing pattern during exercise. In patients, peak VO2 correlated significantly with ISWD (r = 0.80), FVC (r = 0.78), FEV1 (r = 0.73) and ΔVT/ΔlnVE (r = 0.58). We conclude that patients with AIS present significant walking limitation due to impaired pulmonary function and breathing pattern during exercise. This impairment may partialy explain the reluctance of patients with AIS to perform exercises. Thus, walking-based aerobic exercises should be encouraged in these patients. ER -