RT Journal Article SR Electronic T1 Effects of cigarette smoking intensity on functional capacity of active smokers JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1334 VO 42 IS Suppl 57 A1 Rafaella Xavier A1 Dionei Ramos A1 Fernanda Rodrigues A1 Juliana Ito A1 Giovana Bertolini A1 Bruna Spolador A1 Alessandra Toledo A1 Ercy Ramos YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P1334.abstract AB Smokers have increased airflow resistence and reduced exercise tolerance. Aim: To evaluate the effects of smoking intensity on functional capacity of active smokers. Methods: 54 smokers were divided into light (LS) (1-10 cigarettes/day (c/d); n=10), moderate (MS) (11-20 c/d; n=12) and heavy smokers (HS) (³21 c/d; n=32). The smoking behaviour, pulmonary function, and functional capacity (six minutes walk test - 6MWT) were evaluated. The heart rate (HR), peripheral oxygen saturation (SpO2) and systolic (SBP) and diastolic (DBP) blood pressure were evaluated before, immediately and two minutes after recovery the 6MWT. An age-matched non smoker (NS) group (n=13) was also assessed. Comparisons between groups were conducted by Kruskal-Wallis, followed by Dunn’s. For comparison among 6MWT variables, numerical deltas (Δ) were calculated for the HR, SpO2, SBP and DBP Results: MS and HS walked less than NS in 6MWT (P=0,001). HS had lower FEV1 than NS (P=0,003). Furthermore, the HR of NS increased more immediately after 6MWT (P<0,0001) and two minutes after the 6MWT (P<0,0001). The SBP increased more in HS compared to NS after the 6MWT (P=0,005).View this table:Numerical deltas between moments.Conclusion: MS and HS had lower functional capacity than NS and smoking had a bad hemodynamic repercussion in the 6MWT.