PT - JOURNAL ARTICLE AU - Stanislav Gorbunkov AU - Olga Lukina AU - Larisa Kirukhina AU - Vladimir Varlamov AU - Andrey Akopov TI - LVRS in patients with severe emphysema: Relationship between patients age and surgical results DP - 2013 Sep 01 TA - European Respiratory Journal PG - P4336 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P4336.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P4336.full SO - Eur Respir J2013 Sep 01; 42 AB - Introduction: The present study is a retrospective analysis of surgical treatment results for respiratory failure in pulmonary emphysema patients of different age.Methods: Patients with severe emphysema underwent LVRS between 2004 and 2012 were divided into two groups: patients aged 35 years old and younger (group A) and patients aged more than 35 years old (group B). Comparison of clinical data, radiology, functional test, operative reports, early postoperative course and follow-up results was made.Results: Of 123 patients with indication for LVRS (group A-9 patients, group B-114 patients) 69 patients were operated (group A-7 (78%), group B-62 (53%). Average age for group A was 30 y.o.(from 24 to 35) and for group B-54 y.o. (from 41 to 71). Respiratory function disturbances were considerably heavier in group A( FEV1 20% (864ml), RV 368%) than in group B (FEV1 29%(1090ml), RV 229%).In 66 patients unilateral LVRS via thoracotomy was performed, three patients underwent bilateral LVRS via median sternotomy. The average occurrence of postoperative complications was 14% in group A and 42 % in group B (p<0,05). Prolonged air leak was the most common complication (n=19%). Postoperative mortality was 7,2% (n=5) and had place only in group B. The frequency of bacterial exacerbation in first year after operation was 14% in group A and 23% in group B). Positive effect on forced expiration volume lasted in average of 29 months in group A and 27 months in group B).Conclusions: Despite of initially heavier respiratory failure in younger patients LVRS performed in this group is characterised by more favorable early postoperative course and remote follow-up results are comparable in both groups.