PT  - JOURNAL ARTICLE
AU  - Adam Nowinski
AU  - Damian Korzybski
AU  - Beata Bialas-Chromiec
AU  - Dorota Gorecka
TI  - Clara cells protein 16 (CC-16) level correlates with hemoglobin level in COPD patients
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P837
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P837.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P837.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Introduction: Anemia secondary to systemic inflammation is a common co-morbidity associated with COPD. Clara cells secretory protein 16 is potential clinical biomarker of alveolar injury in COPD patients.Aims: The aim of this study was to evaluate the relationships between COPD severity, serum hemoglobin levels, serum CC-16 levels and C-reactive protein.Methods: One center longitudinal prospective study in COPD patients was designed. COPD patients treated in respiratory department were studied. Serum levels of CC-16, C-reactive protein (CRP), hemoglobin (Hb) and iron (Fe) were assessed.Results: 61 COPD patients were analyzed. Results of biochemistry parameters stratified according to GOLD stages and category groups are shown in the table (*p<0.05). Results are means ±SD.View this table:There was significant correlation between CC-16 and Hb (r=0.34, p<0.05) in all group.Conclusions: CC-16 protein is potential biomarker in COPD with unclear possible relationship with anemia in COPD patients.