TY - JOUR T1 - What is the optimum expiratory trigger sensitivity level for patient-ventilator synchrony during NIV in COPD patients? JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - 1976 AU - Cenk Kirakli AU - Ozlem Edipoglu AU - Ilknur Naz AU - Dursun Tatar AU - Fevziye Tuksavul Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/1976.abstract N2 - Aim: Air leaks around the mask during NIV generally cause delayed cycling into expiration, leading to patient-ventilator asynchrony. The aim of this study was to investigate the role of increasing expiratory trigger sensitivity (ETS) on patient-ventilator synchrony during NIV.Methods: Nine COPD patients were enrolled. NIV was performed as pressure support ventilation with an oro-nasal mask. Patient’s respiratory efforts were detected with an esophageal baloon catheter and data were recorded from the RS232 port of the ventilator with a software for 10 minutes in each ETS level (25%, 50%, and 70%) consecutively and compared with each other. The number of nontriggering efforts (NTE) was defined as the difference between the respiratory rate of the patient and the ventilator.Results: Compared to ETS 25%, ETS 50% and 70% reduced NTE (4±3 vs. 0.2±0.4 and 0.7±1 breaths/min respectively, p<0.05).ETS 50% resulted in higher Vt/kg when compared to ETS 25% and 50% (8.5±5 vs 7.4±5 and 7.4±5 ml/kg respectively, p<0.01)Conclusion: Increasing ETS in COPD patients up to 50% seems optimum for improving synchrony under NIV. ER -