RT Journal Article
SR Electronic
T1 Comparison of quality of life in smoking and non-smoking COPD patients in India using St. George's respiratory questionnaire and COPD assessment test
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4908
VO 42
IS Suppl 57
A1 Jyoti Londhe
A1 Bill Brashier
A1 Neha Iyer
A1 Sapna Madas
A1 Sanjay Juvekar
A1 Sundeep Salvi
A1 Peter Barnes
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4908.abstract
AB Quality of life (QoL) assessment is an integral part of disease management and prognosis for all chronic illnesses, including COPD. Non-smoking (NS) COPD accounts for 25-45% of all COPD cases globally, and is relatively more common in India. There is little information on QoL of NS-COPD patients and how it compares with smoking (S)-COPD. We studied the QoL of NS-COPD using SGRQ and CAT and compared it with S-COPD. Methods: 80 smoking & 77 non-smoking physician-confirmed COPD patients with a post-bronchodilator FEV1/FVC<70% were administered SGRQ and CAT using validated locally translated questionnaires. Results: There were no differences in the age and mean FEV1 of S-COPD and NS-COPD (41.0% ± 13.3 vs 42.9% ± 17.4; p=ns). The mean total SGRQ & CAT scores were similar in both the COPD groups (SGRQ: 60.7±18.1 vs 62.6±18.5; p=0.51) (CAT: 23.7±7.3 vs 23.5±8.0; p=0.86). NS-COPD had lesser symptom SGRQ scores and had lesser CAT scores for cough compared with S-COPD (SGRQ 43.6±24.2 Vs 52.5±21.4; p=0.01 and CAT 2.5±1.3 Vs 3.0±1.4; p=0.02). When divided into moderate, severe and very severe COPD, NS-COPD and S-COPD showed similar SGRQ and CAT scores (p>0.05). There was a strong correlation between SGRQ and CAT scores for both NS-COPD (r2= 0.54, p=0.0001) and S-COPD (r2= 0.67, p=0.0001). Interestingly, the SGRQ scores are higher in Indian patients than in Western patients for equivalent FEV1 values. Conclusion: Impairment of QoL of NS-COPD is similar to S-COPD in an Indian cohort.