%0 Journal Article %A Seung Soo Yoo %A Shin Yup Lee %A Keum Ju Choi %A Hyejin Jung %A Mi Jeong Hong %A Jae Yong Park %T RET fusion genes in Korean non-small cell lung cancer %D 2013 %J European Respiratory Journal %P P4511 %V 42 %N Suppl 57 %X Recently, rearranged during transfection (RET) fusion genes have been identified in 1%-2% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we examined the RET fusion status in surgically resected NSCLCs, using a reverse transcriptase polymerase chain reaction. RET fusion genes have been detected in 3 (1.9%) of 156 patients of NSCLC and in 3 (2.9%) of 104 patients of adenocarcnima. Of the 3 fusion genes identified, 2 were KIF5B-RET fusion genes and 1 was CCDC6-RET fusion gene. All the three patients were females and never smokers with adenocarcinomas. RET fusion genes were mutually exclusive with EGFR, KRAS mutations and EML4-ALK fusion. %U https://erj.ersjournals.com/content/erj/42/Suppl_57/P4511.full.pdf