@article {AlizadehP4298, author = {Mehdi Alizadeh and Leila Ghasemi}, title = {The effect of treatment duration by inhaled glucocorticosteroids, on "cough variant asthma" in children}, volume = {42}, number = {Suppl 57}, elocation-id = {P4298}, year = {2013}, publisher = {European Respiratory Society}, abstract = {National Asthma Education and Prevention Program has recommended that: {\textquotedblleft}CVA (cough variant asthma) treatment should follow the stepwise approach to long-term management of asthma.{\textquotedblright} This leads us to deal with CVA, as same as the asthma, and any patient enter to this approach, must use at least 3 months ICS (inhaled glucocorticosteroids). The aim is to examine, is there any significant changes in the outcome of CVA by changing duration of treatment with ICS. Based on inclusion criteria (children 2-12 years with chronic cough as the only symptom and sign of asthma) and exclusion criteria (any signs and symptoms of other diseases that can cause chronic cough other than asthma) 250 children entered in the study and followed for 1 year. Patients randomly allocated in 2 groups (one group treated for 1 month and the other for 3 months). 212 children (130 male and 82 female) completed the study and there was no significant difference in mean age and sex ratio between 2 groups. Patients who received 1 month treatment (113 patients), cough control ratio was 69.7 \% and mean time to next episode of chronic cough was 168.8 days. Patients who received 3 months treatment (99 patients) cough control ratio was 78.8 \% and mean time to next episode was 180.6 days. There were no significant difference in Cough control ratio (P value = 0.09) and cough free time until next episode of chronic cough (P value = 0.4) between 2 groups. Developing wheezy asthma after 1 year were 6.3\% between patients who treated for 1 month and 9\% in other group (P value=0.8). Increasing CVA treatment time from 1 month to 3 months, with low dose ICS does not alter the cough control ratio and cough free time.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/42/Suppl_57/P4298}, eprint = {https://erj.ersjournals.com/content/42/Suppl_57/P4298.full.pdf}, journal = {European Respiratory Journal} }