RT Journal Article
SR Electronic
T1 Prevalence of obesity hypoventilation syndrome in OSA patients in the UAE
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4050
VO 42
IS Suppl 57
A1 Ashraf Al Zaabi
A1 Salahudeen Fizal
A1 M.K. Rafeek
A1 Nico Nagelkerke
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4050.abstract
AB Study objectives: Obesity causing hypoventilation in OSA patient has been termed Obesity Hypoventilation Syndrome (OHS). A retrospective analysis was done to find the Prevalence of OHS in diagnosed Obstructive Sleep Apnea (OSA) patients. Comorbidities like Diabetes (DM), Hypertension (HT), ischemic Heart disease (IHD), and pulmonary hypertension were also assessedDesign: Descriptive analysis of retrospectively collected clinical data of patients who underwent a sleep study during March 2008 – June 2009.Setting: Sleep disorder centre of tertiary level military hospitalView this table:Results: 215underwent sleep study. 107 (85 males and 22 females) had OSA (AHI > 5/hr).16.8% of OSA patients (18 /107) were diagnosed to have OHS, 31.8% of females (7/22, p= 0.05) and 13% (11/85, p= .052, Fisher’s exact test) of males. The females tended to be older with a mean age of 60yrs versus 48 for males.Adjusted for sex, using the Mantel-Haenzel test, OHS was significantly associated with hypertension with an OR of 3.5 (p= 0.030, 95% CI 1.19- 10.33) and DM with an OR of 4.6 (p= 0.017, 95% CI of 1.39 – 15.4), as well as with IHD with an OR of 5.09 (p = 0.036, 95% CI 1.21-21.35).Pulmonary hypertension and OHS: 6 OHS patients had PHT, (RVSP 25mm Hg at rest by echo). with sex adjusted OR of 16.1 (95%CI of 3.2 – 82.0).Conclusions: Prevalence of OHS was 16.8% There was a strong association between OHS, cardiovascular comorbidities, diabetes & PHT.1 Oslone AL, et al OHS Am J Med 2005; 118:948 -562 Hida W (2003) Quality of life in OHS Sleep Breath 7:1–2.