RT Journal Article
SR Electronic
T1 Differences in adherence to common inhaled medications in COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4137
VO 42
IS Suppl 57
A1 Kirsten Koehorst-ter Huurne
A1 Kris Movig
A1 Paul vanderValk
A1 Job van der Palen
A1 Marjolein Brusse-Keizer
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4137.abstract
AB Objective: To study differences in adherence to common inhaled medication in COPD.Methods: Therapy adherence of 795 patients was recorded from pharmacy records over 3 years. It was expressed as percentage and deemed good at 75–125%, sub-optimal 50-75%, and poor <50% or >125%. Some patients used more than one medication, so we present 1377 medication periods.Results: The percentages of good adherence ranged from 43.2 (beclometason) - 75.8% (tiotropium); suboptimal from 2.3 (budesonide) - 23.3% (fluticasone); <50% from 4.4 (formoterol/budesonide) – 18.2% (beclometason); and >125 from 5.1 (salmeterol) - 38.6% (budesonide). (table 1)View this table:Table 1: Number (%) of patients in the adherence subgroupsConclusion: Tiotropium showed the highest adherence, followed by ciclesonide, both dosed once daily. Adherence with solely salmeterol and fluticason is higher than the combined preparation. For formoterol/budesonide adherence is better than budesonide alone. The idea of improving adherence by using combined preparations cannot be confirmed in this study.