PT - JOURNAL ARTICLE AU - Kirsten Koehorst-ter Huurne AU - Kris Movig AU - Paul vanderValk AU - Job van der Palen AU - Marjolein Brusse-Keizer TI - Differences in adherence to common inhaled medications in COPD DP - 2013 Sep 01 TA - European Respiratory Journal PG - P4137 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P4137.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P4137.full SO - Eur Respir J2013 Sep 01; 42 AB - Objective: To study differences in adherence to common inhaled medication in COPD.Methods: Therapy adherence of 795 patients was recorded from pharmacy records over 3 years. It was expressed as percentage and deemed good at 75–125%, sub-optimal 50-75%, and poor <50% or >125%. Some patients used more than one medication, so we present 1377 medication periods.Results: The percentages of good adherence ranged from 43.2 (beclometason) - 75.8% (tiotropium); suboptimal from 2.3 (budesonide) - 23.3% (fluticasone); <50% from 4.4 (formoterol/budesonide) – 18.2% (beclometason); and >125 from 5.1 (salmeterol) - 38.6% (budesonide). (table 1)View this table:Table 1: Number (%) of patients in the adherence subgroupsConclusion: Tiotropium showed the highest adherence, followed by ciclesonide, both dosed once daily. Adherence with solely salmeterol and fluticason is higher than the combined preparation. For formoterol/budesonide adherence is better than budesonide alone. The idea of improving adherence by using combined preparations cannot be confirmed in this study.