RT Journal Article
SR Electronic
T1 Gender differences in patients treated for pulmonary tuberculosis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2854
VO 42
IS Suppl 57
A1 Mikhail Chushkin
A1 Sergey Mandrykin
A1 Eduard Tikhokhod
A1 Andrey Belevskiy
A1 Natalia Meshcherykova
A1 Sergey Smerdin
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P2854.abstract
AB Worldwide, tuberculosis is more prevalent in men than in women. The aim of the study was to define any gender-related differences in patients diagnosed and treated for pulmonary tuberculosis.Methods: In 52 FEV1-matched women and men with FEV1 65,5% and 65,4% (p>0.05) who were treated for pulmonary tuberculosis and observed at local dispensaries. We compared age, body mass index (BMI), dyspnea, health-related quality of life.Results: Women had the same age (53,8 vs. 53,1; p> 0.05); the same BMI (24,4 vs. 23,2; p > 0.05); the same MRC (2,11 vs. 2,04; p > 0.05). In females and males FEV1/FVC was 0,68 vs. 0,63 (p<0.05); Saint George’s Respiratory Questionnaire (SGRQ) Symptoms scores were 32,7 vs. 36,3% (difference was -3,6 points; p>0.05); SGRQ Activity scores were 40,2 vs. 34,3% (difference was 5,9 points ; p>0.05); SGRQ Impact scores were 26,5 vs. 20,5% (difference was 6,0 points ; p>0.05); SGRQ Total scores were 31,4 vs. 27,2% (difference was 4,2 points; p>0.05); UCSD Shortness of Breath Questionnaire scores were 23,0 vs 18,9% (difference was 4,1 points; p>0.05). All SF-36 components did not differ between women and men (PF 64,3 vs. 72,8%; RP 52,2 vs. 56,2%; BP 63,7 vs. 68,3%; GH 54,7 vs. 50,5%; VT 56,6 vs. 60,5%; SF 77,5 vs. 80,4%; RE 62,1 vs. 67,5%; MH 60,9 vs. 66,4%; p>0.05 for all).Conclusion: Comparisons matched by predicted FEV1 showed that women had worse health status, reflected in worse SGRQ scores. More attention should be paid to the determinants of QoL in women treated for pulmonary tuberculosis.SGRQ was more sensible than SF-36 in assessment of QoL.