TY - JOUR T1 - Long term reduction of blood pressure in young and elderly hypertensive patients with sleep apnea syndrome treated with CPAP JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2557 AU - Andra Elena Malaut AU - Oana Claudia Deleanu AU - Anca Donoaica AU - Ruxandra Ulmeanu AU - Florin Dumitru Mihaltan Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2557.abstract N2 - INTRODUCTION: Guidelines added obstructive sleep apnea(OSA) as important cause of hypertension(HT) but the reduction of blood pressure(BP) values under CPAP treatment is controversial,without long term follow up.AIM: We studied difference between young(< 60 years) vs elderly(≥ 60 years) patients with OSA and HT regarding BP variation, measured by sphygmomanometer and ambulatory blood pressure monitoring(ABPM), after 3 and 6 months of CPAP treatment.METHOD: We applied exclusion criteria(hypoventilation syndromes, respiratory dysfunctions, other secondary HT, modifying treatment during study, noncompliant patients) to 96 patients(Chi test,T-test).RESULTS: We studied remaining 30 patients:14 young ,16 elderly, without significant differences regarding AHI and somnolence. Diastolic BP(DBP) measured by sphygmomanometer was significantly lower after CPAP treatment in young (from 85.0±12.5 to 71.4±6.9mmHg,p=0.028 after 3 months, to 70.0±7.0mmHg,p=0.038 after 6 months),without differences regarding systolic blood pressure(SBP). Elderly had a reduction in SBP (knowing to be connected with age) and DBP after 3 months(from 141.2±8.3 to 123.6±15.9mmHg,p=0.019, respectively from 80.0±9.2 to 66.2±7.4mmHg, p=0.006),without any differences after 6 months of CPAP. Measured by ABPM elderly patients had a significant decrease only of minimum nocturnal values of DBP from 55.3±6.3 to 47.5±5.7mmHg after 3 months, p=0.021. There was no modification regarding the dipper pattern at 3 or 6 months.CONCLUSION: There is a significant reduction in DBP in both young and elderly OSA patients under CPAP treatment measured by sphygmomanometer only, more pronounced in the first 3 months. ER -