TY - JOUR T1 - Does 6 minute walk test predict nocturnal oxygen desaturation in COPD patients? JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2153 AU - Sinem Iliaz AU - Tulin Cagatay AU - Zuleyha Bingol AU - Gulfer Okumus AU - Goksen Kuran AU - Raim Iliaz AU - Aysen Dokme AU - Fatma Comce AU - Esen Kiyan AU - Zeki Kilicaslan AU - Turhan Ece AU - Penbe Cagatay Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2153.abstract N2 - INTRODUCTION: Patients with chronic obstructive pulmonary disease (COPD) who have nocturnal oxygen desaturation (NOD) should be treated with nocturnal oxygen therapy (NOT) for avoiding morbidity and mortality. Nocturnal oximetry is an expensive and time consuming test that used for evaluating NOD individuals.AIM: To evaluate whether desaturation during 6-minute walk test (6MWT) is useful for predicting NOD in COPD.METHODS: Stable moderate or severe COPD patients were enrolled in this study. Spirometry and carbon monoxide diffusion test (DLCO), arterial blood gas analysis, 6MWT and nocturnal oximetry were performed. Patients with obstructive sleep apnea, hypoxemic respiratory failure, and who were receiving noninvasive mechanical ventilation therapy were excluded.RESULTS: Totally 61 patients (55 male, age: 65.8±8.4) were analysed. Thirty of them had moderate and the others (n=31) had severe COPD. Forced expiratory volume 1 second was 1352±348ml (51.2%±11.8%). Patients who were desaturated during 6MWT had significantly lower DLCO, PaO2, SaO2 and higher PaCO2 levels than the patients who did not desaturated (p<0.001, p=0.001, p=0.001, p=0.02). NOD was more common in severe COPD patients or the patients with higher CO2 levels (p=0.02, p=0.001). Four patients (13%) with moderate COPD were desaturated during 6MWT, however they did not have NOD. Five (33%) of severe COPD patients who were desaturated during 6MWT(n=15) also had NOD. Moderate correspondence was found between 6MWT and NOD in severe COPD patients (Kappa=0.39, p<0.05).CONCLUSION: 6MWT can be recommended as a simple, cheap tool for predicting NOD and selecting individuals for NOT particularly in severe COPD. ER -