TY - JOUR T1 - Incidence and prevalence of non tuberculous mycobacteria [NTM] in adult CF population: A large adult CF centre experience JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P1174 AU - Arunesh Kumar AU - Christine Etherington AU - D.G. Peckham Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P1174.abstract N2 - IntroductionIncidence of Non Tuberculous Mycobacterial [NTM] pulmonary infection has been increasing among Cystic Fibrosis patients reflecting the increase in longevity of such patients as well as the environmental exposure to various species of mycobacteria and possible association with antibiotics use.AimsTo find out the incidence and prevalence of different non tuberculous mycobacteria in patients with cystic fibrosis.Patients and methodsAll Patients with Adult cystic fibrosis who are in clinic follow up were included. We searched our CF database to get information on the sputum microbiology on different culture positive NTM between 2007 and 2012. We also looked for type and frequency of different NTM cultured over this period.ResultsA total of 403 patients were included, male 226[56%] and female 177[44%]. The overall prevalence of NTM in our CF population is 62 out of 403[ 15.38%] increasing from 18 out of 335[5.37%] in 2007.Among NTM, M.Avium Complex[MAC] is most common with prevalence of 27 out of 62 [43%], followed by M.abscessus 22 out of 62[35%]. M.Chelonae accounts for 19/62[30%], M.Kansasi 2/62[3%] and M.Fortuitum 1/62[1.62%]. Incidence of M.Abscessus infection has doubled from 1.49 % in 2007 to 2.72% in 2012 but the incidences of all other NTM have reduced.ConclusionCo-infection with NTM is emerging as a significant problem in adult CF Population. Incidence of M.abscessus infection is increasing, posing a management challenge for pulmonary exacerbations in CF population. ER -