TY - JOUR T1 - Physiological characteristics of high-frequency one-lung ventilation in thoracic surgery JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P4961 AU - Mikhail Kontorovich AU - Serghey Skornyakov AU - Igor Medvinsky AU - Dmytry Eremeev AU - Dmytry Eremeev Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P4961.abstract N2 - INTRODUCTION. We believe no alternative use during operations in the light of high-frequency jet ventilation. HFJV provides excellent oxygenation of arterial blood in the lungs supports expanded position without the use of recruitment-maneuver, increases venous return and cardiac output, reducing intrapulmonary shunting.MATERIALS AND METHODS. The two groups are comparable (in terms of volume of surgery, comorbidities, age) of 50 patients compared the parameters of gas exchange and hemodynamics in patients undergoing surgery for lung during one-lung convective (OCMV) and one-lung high-frequency (OHFJV) ventilation.RESULTS. Results of the study demonstrated a reduction in OHFJV versus OCMV: PIP - to 26,5%; Pes - by 81.6%, PVR - by 41.7%; Qs/Qt - by 45.5% and the increase in PaO2 – 66. 1%, MI - by 91.0%; VA - by 47.8%, CVP - by 28.3% while maintaining the normal pH of 7.42 and PaCO2 = 34.5 mm Hg.CONCLUSIONS. Under conditions of OHFJV, even a complete atelectasis of one lung does not go along with a considerable disorder of gas exchange in contrast to OCMV. This enabled a wider application of this kind of ventilation for lung surgeries on patients with distinct gas exchange and hemodynamics disorders. ER -