TY - JOUR T1 - Usefulness of nasal provocation test in the diagnosis of mite allergic rhinitis: Standard or rapid? JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P904 AU - Céline Lutz AU - Jean-Jacques Braun AU - Frédéric de Blay Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P904.abstract N2 - Introduction:Diagnosis of mite allergic rhinitis is often difficult. Limited studies of Standard Nasal Provocation Test (SNPT) against mites have shown that 13 to 30 % of rhinitics sensitized to mite had a negative NPT. Moreover, SNPT is time consuming and impractical in routine.Objective :Determine the sensitivity and specificity of SNTP, and compare it to the "rapid" nasal provocation test (RNTP).Materials and Methods :91 patients with allergic rhinitis (52 sensitized to mites and 39 controls sensitized to other allergens or non atopic) were included mean age of 26 years. All patients had a SNTP and a RNTP separated at least for 4 weeks with Stallergènes Dpt extracts (Der p 1 content: 7.9 mg / ml for 100 IR)The SNTP was positive if the nasal resistance increased more than 100% and / or if the clinical score was more than 5 points (score of Lebel-Bousquet). The RNTP was positive if the (Lebel Bousquet score) was greater than 5 points.Results :27 men and 64 women were included. Skin prick tests to Dpt was 6.8 mm (+ / - 2.6). The duration of SNTP averaged 4 hours and 30 minutes for RNTP. The sensitivity and specificity of SNTP were the same, 94.4%. RNTP sensitivity was lower (83.7%). No serious side effects occurred with the 2 tests.Conclusion :1) We have validated SNRP in a young population susceptible to be candidate for immunotherapy.2) RNTP could replace SNTP with less sensitivity, with no safety issue.3) Could become a tool for pulmonologist to select patients for desentization to mite.Study supported by Stallergènes Laboratories ®. ER -