RT Journal Article
SR Electronic
T1 Prognostic scores in pulmonary embolism: PESI, simplified PESI or PREP?
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4100
VO 42
IS Suppl 57
A1 Jose Luis Lobo
A1 Veronica Saray Hernandez Garcia
A1 Agustina Rivas Guerrero
A1 Julia Amaranta Garcia Fuertes
A1 David Bravo Blanco
A1 Aitor Ballaz Quincoces
A1 Dolores Nauffal Manzur
A1 Remedios Otero Candelera
A1 Reina Valle Bernard
A1 David Jimenez De Castro
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P4100.abstract
AB INTRODUCTIONWhen evaluating the prognosis of hemodinamically stable pulmonary embolism (HSPE), clinical scores (PESI, sPESI) have demonstrated their useful to select low risk patients, but are insufficient to classify high risk patients that could benefit from fibrinolytic treatment. Recently, the PREP score, that includes not only clinical variables but also BNP and echocardiographic RV/LV ratio, has been described and could be useful to select both low and high risk patientsAIMS1 Validate the PREP score in a wide sample of patients with HSPE2 Compare the prognostic value of the PREP score with PESI and sPESIMETHODSPROTECT is a prospective multicentre study that has included patients with HSEP. Clinical and echocardiographic variables have been measured along with ventricular diameter in angioTC, I troponin and BNP levels. Patients were followed up 30 days. PESI, sPESI and PREP were calculated with these dataRESULTS848 patients were included (50.9% female, mean age 67,5 ± 16.7) Global mortality at day 30 was 4.5% (n=38)CONCLUSIONS1 Although the NPV for mortality of the three scores were high, it may due to the low prevalence because the respective sensibilities of PESI and sPESI compared with PREP score resulted significantly different2 Although PPV is limited because of the low frecuency of events, the specifity of PREP score is very high and could be valid for the selection of patients susceptible to fibrinolytic treatment.