RT Journal Article
SR Electronic
T1 Median survival in unselected patients with idiopathic pulmonary fibrosis in the United Kingdom
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3819
VO 42
IS Suppl 57
A1 Wasim Jamal
A1 Charlotte Wottons
A1 Ghazi Mirani
A1 Noeleen Foley
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P3819.abstract
AB Introduction and Objectives:The median survival of patients with UIP/IPF is reported in several series as 3 years. Anecdotally, many respiratory physicians have patients who remain stable for many years. We examined median survival and cause of death in our patients diagnosed with IPF in the year 2006 and 2007 attending a large general hospital in the UK.Methods:Twenty patients were selected by retrospective data collection from our ILD clinic records; diagnosis was established on HRCT and confirmed by consultant radiologist and pulmonologist with special interest and expertise in interstitial lung disease. Patient functional status, pulmonary function at diagnosis and follow up, treatment; and cause of death from death certificates were recorded.Results:Median survival was 27.1 months (range 1.8-76.2, SD 24.3). FVC at Diagnosis: Mean 81% (range 43-120%, SD 22.8). FVC at diagnosis was predictive of survival.View this table:Table 1: FVC (%) at diagnosis and median survivalPulmonary fibrosis was listed as primary (29%) or secondary (35%) cause of death in 64%. Other causes are listed inView this table:Table 2: Causes of death of 17 patients *Conclusion:Median survival in our unselected population was 27.1 months. IPF was the leading cause of death. FVC at diagnosis was predictive of survival. Patients on omeprazole had better median survival.