PT  - JOURNAL ARTICLE
AU  - Marijke Amelink
AU  - Reinier Wener
AU  - Lucia Rijssenbeek-Nouwens
AU  - Martine Kruijtbosch
AU  - Marcel Bouvy
AU  - Elisabeth Bel
TI  - Poor adherence to ICS treatment in patients with chronic respiratory diseases
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P4900
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P4900.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P4900.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - RationaleOne of the major causes of treatment failure in respiratory diseases is non-adherence to treatment. Adherence rates in patients with severe airway disease are scarceAimTo assess non-adherence to inhaled corticosteroids (ICS) in patients with severe airway disease in a large cohort of primary and secondary care patients and to assess factors associated with very poor adherenceMethodsAll patients (>18yr) prescribed ICS 1000ug fluticason eq. or 500ug plus chronic oral corticosteroids were selected from 47 community pharmacies. Data contained all prescription drugs dispensed in 2011. Patients were asked to complete questionnaires on demographics and the Asthma Control Questionnaire (ACQ). Adherence was defined as very poor (<50%), poor (50-80%), adherent (80-100%) or overuse (>100%)Results1850 out of 5002 patients completed the questionnaires. After exclusion of 664 patients with controlled disease (ACQ≤1.5), 38% were labelled as difficult-to-treat asthma, 33% as mixed asthma/COPD, 24% as COPD and 5% as other respiratory disease. Adherence rates are given in table1. Factors associated with very poor adherence were: being treated by primary care, younger age and a diagnosis of other respiratory disease. In asthma, very poor adherence was associated with being treated by primary care, and in mixed asthma/COPD with current smoking. In COPD and other respiratory diseases no associations were foundConclusionPoor adherence is a significant problem in chronic severe airway disease. Therefore, adherence rates should be thoroughly checked and addressed.View this table: