RT Journal Article
SR Electronic
T1 The prevalence and determinants of COPD in an urban community in Lagos, Nigeria
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P933
VO 42
IS Suppl 57
A1 Obianuju Ozoh
A1 Bolanle Balogun
A1 Olapeju Oguntunde
A1 Chioma Nwizu
A1 Alero Roberts
A1 Victor Inem
A1 Olarenwaju Bandele
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P933.abstract
AB Background: There is limited data on the prevalence of COPD in sub-Saharan Africa. We aimed to determine the prevalence of COPD in an urban community in Lagos, Nigeria and also explore the risk factors associated with COPD.Methods: Adults 40 years and above were randomly selected from Idi-Araba community in Mushin Local Government Area. Questionnaire of symptoms and risk factors for COPD was completed and pre-bronchodilator spirometry performed on all participants. Those with pre-bronchodilator FEV1/FVC ratio <0.7 initially also had post bronchodilator spirometry performed after inhalation of 200ug salbutamol. A diagnosis of COPD was defined as post-bronchodilator FEV1/FVC ratio <0.7. Multivariate logistic regression analysis was used to explore the significant determinants of COPD and the magnitude of risk expressed as odds ratio (OR).Results: There were 412 participants (58.3%) females. Mean age was 53.7±11.2 years, 9.7% had >12 years of formal education, 13.8% were ever smokers (1.5% current smokers), 23.1% used biomass fuel for cooking, 24.5% had occupational dust exposure, and 1.5% had tuberculosis previously. The prevalence of COPD was 5.3% (95% confidence interval (CI) 3.4 – 8.0), 7.6% (95% CI 4.1 – 12.6) in males, 3.8% (95% CI 1.7 – 7.0) in females, (X2=2.88, p=0.09). The significant determinants of COPD were ever smoking cigarettes (OR 4.9 95% CI 1.8-13.2, p=0.001) and increasing age, (OR for age ≥60 years 3.6, 95%CI 1.4-9.5 and OR for age >70 years 4.6, 95%CI 1.6-13.0, p=0.004).Conclusion: The prevalence of COPD in our population is substantial. Tobacco control should be a priority in reducing the prevalence of COPD in our region.